
Summary:
- Garlic
- Shallot
- Citrus fruits (blood orange>orange>lemon>lime>grapefruit)
- Peppermint
- Nettle tea
- Cinnamon
- Green tea
Mannose Binding Lectins:
These proteins potentially stick to the S proteins on the surface of the virus. This activates the innate immune system to attack the virus. It may also block the virus from binding to ACE2 to enter the cells.
- Griffithsin (Red algae)
- Garlic
- Shallot
- Chive
ACE2 Binders (only studied in vitro):
S proteins on the virus bind to ACE2 on the surface of the lung cells, which results in entry into the cell.
- Chinese skullcap
- Hesperetin (blood oranges, lemon, lime, grapefruit)
- Soy
- Licorice root
- Astragalus
- Stinging nettle
- Andrographis
- Sambucus
Serine protease inhibitors:
This is a co-enzyme needed for the ACE2 enzyme to function in allowing viral entry into the cell.
- Garlic
- Milk thistle
- Quercetin
Endocytosis inhibitors:
This is when the viral envelope fuses with our cell membrane, spilling the viral genome into our cell.
- Cinnamon
References:
The Journal of Infectious Diseases, Volume 191, Issue 10, 15 May 2005, Pages 1697–1704. Mannose-Binding Lectin in Severe Acute Respiratory Syndrome Coronavirus Infection. W. K. Eddie Ip et al. https://doi.org/10.1086/429631
https://academic.oup.com/jid/article/191/10/1697/789682
Purification and characterization of a mannose-specific lectin from Shallot (Allium ascalonicum) bulbs. Mo H1, Van Damme EJ, Peumans WJ, Goldstein IJ.
https://www.ncbi.nlm.nih.gov/pubmed/8215447
New mannose-binding lectin isolated from the rhizome of Sarsaparilla Smilax glabra Roxb. (Liliaceae). Ooi LS1, Sun SS, Wang H, Ooi VE.
https://www.ncbi.nlm.nih.gov/pubmed/15453671
New mannose-specific lectins from garlic (Allium sativum) and ramsons (Allium ursinum) bulbs. Kaku H1, Goldstein IJ, Van Damme EJ, Peumans WJ.
https://www.ncbi.nlm.nih.gov/pubmed/1394291
Possible inhibitors of ACE2, the receptor of 2019-nCoV. Chuanbo Huang et al. file:///Users/starrramson/Downloads/preprints202002.0047.v1.pdf
Potential natural compounds for preventing 2019-nCoV infection. Hansen Chen 1 *, Qiaohui Du 2* file:///Users/starrramson/Downloads/preprints202001.0358.v1.pdf
Procyanidins and butanol extract of Cinnamomi Cortex inhibit SARS-CoV infection. Zhuang M et al.
